Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | GJB2 | P29033 | 3/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573455 | 1.00 | PTPN1 (0.47) | PTPN1PTPN2PTPN6PTPN11SSTR1 | |
| SCHEMBL8576622 | 1.00 | PTPN1 (0.47) | PTPN1PTPN2PTPN6PTPN11SSTR1 | |
| SCHEMBL15833434 | 0.92 | PTPN1 (0.48) | PTPN1PTPN2PTPN11TSHRALDH1A1 | |
| SCHEMBL16299427 | 0.92 | PTPN1 (0.48) | PTPN1PTPN2PTPN11TSHRALDH1A1 | |
| SCHEMBL17850338 | 0.90 | PTPN1 (0.49) | PTPN1PTPN2PTPN11TSHRLMNA | |
| SCHEMBL26822757 | 0.90 | PTPN1 (0.49) | PTPN1PTPN2PTPN11TSHRLMNA | |
| SCHEMBL8576619 | 0.89 | LGALS9 (0.46) | PTPN1TSHRALDH1A1LMNA | |
| SCHEMBL8577941 | 0.89 | LGALS9 (0.46) | PTPN1TSHRALDH1A1LMNA | |
| SCHEMBL8576095 | 0.89 | LGALS9 (0.46) | PTPN1TSHRALDH1A1LMNA | |
| SCHEMBL8573452 | 0.89 | LGALS9 (0.46) | PTPN1TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998016537-A1 | NOVEL COMPOUNDS | ASTRA AKTIEBOLAG (PUBL) (SE) | 1998-04-23 | — | — | WO | disclosed |