Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578663 | 0.92 | KMT2A (0.47) | MEN1KMT2AACHEMAOBALDH1A1 | |
| SCHEMBL8573465 | 0.87 | KMT2A (0.49) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL8803534 | 0.85 | MAOB (0.48) | ACHEMAOB | |
| SCHEMBL8575194 | 0.84 | KMT2A (0.55) | MEN1KMT2AMAOBALDH1A1HPGD | |
| SCHEMBL8798715 | 0.84 | NPC1 (0.46) | ACHEMAOBTDP1RAB9AROCK2 | |
| SCHEMBL8575290 | 0.80 | KMT2A (0.50) | MEN1KMT2AALDH1A1HPGDHTT | |
| SCHEMBL8577745 | 0.79 | KMT2A (0.48) | MEN1KMT2AMAOBALDH1A1HPGD | |
| SCHEMBL8578675 | 0.79 | KMT2A (0.49) | MEN1KMT2AMAOBALDH1A1HPGD | |
| SCHEMBL8576909 | 0.77 | ROCK2 (0.44) | MEN1KMT2AMAOBALDH1A1LMNA | |
| SCHEMBL9171923 | 0.77 | ROCK2 (0.44) | MEN1KMT2AMAOBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710152-A | ANTIDIABETIC, ANTILIPEMIC, AND HYPOGLYCEMIC AGENTS; DIETETICS | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |