Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HEXA | P06865 | 1/20 | 0.40 |
| ▸ | HEXB | P07686 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.37 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797253 | 0.86 | RAB9A (0.41) | ALDH1A1HPGDHEXAHEXBNPC1 | |
| SCHEMBL8575194 | 0.82 | KMT2A (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8572986 | 0.80 | DRD2 (0.39) | KMT2AMEN1ALDH1A1MAPTABCB1 | |
| SCHEMBL8578663 | 0.80 | KMT2A (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8575327 | 0.80 | MEN1 (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8573465 | 0.77 | KMT2A (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8577745 | 0.77 | KMT2A (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8797532 | 0.76 | MEN1 (0.52) | KMT2AMEN1HPGDGAA | |
| SCHEMBL8797533 | 0.76 | MEN1 (0.52) | KMT2AMEN1HPGDGAA | |
| SCHEMBL8578675 | 0.75 | KMT2A (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710152-A | ANTIDIABETIC, ANTILIPEMIC, AND HYPOGLYCEMIC AGENTS; DIETETICS | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |