Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 5/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576286 | 0.75 | DPP4 (0.39) | MAPTTSHRALDH1A1POLBHPGD | |
| SCHEMBL8575572 | 0.74 | DPP4 (0.36) | TSHRDPP4LTA4H | |
| SCHEMBL12964717 | 0.71 | LTA4H (0.50) | MAPTTSHRALDH1A1POLBHPGD | |
| SCHEMBL8576633 | 0.70 | ALDH1A1 (0.45) | MAPTALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL8157406 | 0.70 | ALDH1A1 (0.42) | MAPTALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL27986344 | 0.70 | ALDH1A1 (0.42) | MAPTALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL12964715 | 0.69 | DPP4 (0.52) | MAPTTSHRALDH1A1POLBHPGD | |
| SCHEMBL498602 | 0.69 | DPP4 (0.65) | MAPTTSHRALDH1A1POLBHPGD | |
| SCHEMBL498784 | 0.69 | DPP4 (0.45) | MAPTALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL8575706 | 0.68 | ALDH1A1 (0.44) | MAPTTSHRALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753692-A | PLANT EXTRACTS, IMMUNOSTIMULANTS TREATING IMMUNODEFICIENCY DISEASES | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1998-05-19 | — | — | US | disclosed |
| US-5747525-A | ANTITUMOR AGENTS OF OLIGOMERS OF THIOPHENE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1998-05-05 | — | — | US | disclosed |
| US-5602170-A | ADMINISTERING ANTIIFLAMMATORY AGENT | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1997-02-11 | — | — | US | disclosed |