Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574701 | 0.87 | QPCT (0.41) | QPCTEGFRRETKDRPPARG | |
| SCHEMBL8427269 | 0.85 | EGFR (0.43) | QPCTEGFRRETKDRPPARG | |
| SCHEMBL8306914 | 0.83 | CYP1B1 (0.43) | QPCTEGFRRETKDRPPARG | |
| SCHEMBL8431649 | 0.82 | CYP1B1 (0.51) | EGFRPPARGCYP1B1CYP1A1XDH | |
| SCHEMBL8304422 | 0.82 | CYP1B1 (0.63) | KDRCYP1B1CYP1A1XDHIP6K2 | |
| SCHEMBL8306264 | 0.82 | CYP1B1 (0.63) | PPARGCYP1B1CYP1A1XDHIP6K2 | |
| SCHEMBL8431650 | 0.81 | EGFR (0.44) | QPCTEGFRRETKDRCYP1B1 | |
| SCHEMBL8305061 | 0.81 | CYP1B1 (0.59) | EGFRRETKDRPPARGCYP1B1 | |
| SCHEMBL8306988 | 0.80 | CYP1B1 (0.42) | QPCTEGFRRETKDRPPARG | |
| SCHEMBL8306597 | 0.79 | ABCB1 (0.42) | QPCTPPARGMAOBABCB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792789-A | TREATING HYPERPERMEABILITY AND INFLAMMATION | ADIR ET COMPAGNIE (FR) | 1998-08-11 | — | — | US | disclosed |