Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304673 | 0.91 | BRD4 (0.40) | ABCB1BRD4MAOBMAOAMEN1 | |
| SCHEMBL8307532 | 0.89 | L3MBTL1 (0.39) | ABCB1BRD4MAOBMAOAMEN1 | |
| SCHEMBL8431005 | 0.87 | HPGD (0.50) | BRD4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8306914 | 0.86 | CYP1B1 (0.43) | ABCB1MAOBMAOAMEN1KMT2A | |
| SCHEMBL8427269 | 0.84 | EGFR (0.43) | ALDH1A1KDM4EQPCTPPARG | |
| SCHEMBL8307688 | 0.83 | MAPT (0.35) | BRD4MAOBMAOAMEN1KMT2A | |
| SCHEMBL8310185 | 0.83 | MAOB (0.41) | ABCB1BRD4MAOBMAOAMEN1 | |
| SCHEMBL8572731 | 0.82 | QPCT (0.38) | ABCB1MAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL8309092 | 0.82 | ABCB1 (0.52) | ABCB1MAOBMAOAMEN1KMT2A | |
| SCHEMBL8309192 | 0.82 | CYP3A4 (0.39) | BRD4MAOBMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709383-B1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-15 | — | — | EP | disclosed |
| US-5629339-A | CHRONIC VENOUS INSUFFICIENCY | ADIR ET COMPAGNIE (FR) | 1997-05-13 | — | — | US | disclosed |
| EP-0709383-A1 | Diosmetin derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-01 | — | — | EP | disclosed |