Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.35 |
| ▸ | CDK1 | P06493 | 5/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.34 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.34 |
| ▸ | DHFR | P00374 | 3/20 | 0.34 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.34 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.34 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.34 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3172914 | 0.84 | TLR8 (0.33) | TLR8CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL6705148 | 0.80 | TLR8 (0.34) | TLR8TLR7PIK3CDPIK3R1PIK3CA | |
| SCHEMBL17956087 | 0.79 | TLR8 (0.31) | TLR8CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL8727256 | 0.77 | TLR8 (0.40) | TLR8CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL8727251 | 0.76 | ELANE (0.39) | TLR8CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL30612923 | 0.72 | TLR8 (0.51) | TLR8CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL25958200 | 0.71 | ELANE (0.46) | TLR8DHFRDCPSPIN1CSNK1A1 | |
| SCHEMBL21712343 | 0.71 | ABL1 (0.59) | TLR8DHFRDCPSABL1RAD52 | |
| SCHEMBL30612922 | 0.71 | TLR8 (0.49) | TLR8CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL5139045 | 0.70 | ABL1 (0.32) | ABL1RAD52RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741909-A | PHARMACEUTICAL COMPOSITIONS WHICH ACT AS ANTIVIRAL AGENTS, INDUCE BIOSYNTHESIS OF INTERFERON AND INHIBIT TUMOR FORMATION IN ANIMALS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-21 | — | — | US | disclosed |