Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17956087 | 0.86 | TLR8 (0.31) | TLR8PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3172914 | 0.81 | TLR8 (0.33) | TLR8 | |
| SCHEMBL6278527 | 0.80 | TLR8 (0.39) | TLR8TLR7 | |
| SCHEMBL8575636 | 0.80 | TLR8 (0.35) | TLR8PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL8727256 | 0.80 | TLR8 (0.40) | TLR8PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL8727251 | 0.77 | ELANE (0.39) | TLR8PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL18587567 | 0.74 | TLR8 (0.43) | TLR8 | |
| SCHEMBL25958200 | 0.72 | ELANE (0.46) | TLR8PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL5139045 | 0.71 | ABL1 (0.32) | — | |
| SCHEMBL8571306 | 0.70 | PARP1 (0.46) | PIK3CGPIK3CDADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014754-A1 | Urea substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014754-A1 | Urea substituted imidazoquinolines | IFNG, EIF2AK2, IRF3 | TLR8 237/4885PIK3CG 3266/4885PIK3CD 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.