Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1587932 | 0.93 | DPP4 (0.43) | HTR2CMCHR1DPP4OPRL1CTSC | |
| Hydrochloric Acid SCHEMBL3561180 | 0.91 | DPP4 (0.42) | HTR2CMCHR1DPP4OPRL1CTSC | |
| SCHEMBL737193 | 0.82 | DPP4 (0.42) | HTR2CDPP4AVPR1ANR3C2 | |
| Butane SCHEMBL8604221 | 0.81 | SIGMAR1 (0.50) | AVPR1A | |
| SCHEMBL4977596 | 0.78 | KDM1A (0.40) | HTR2CDPP4OPRL1KDM1A | |
| SCHEMBL1588901 | 0.77 | AVPR1A (0.38) | CTSCKDM1AAVPR1ASLC5A1SLC5A2 | |
| Butane SCHEMBL8569562 | 0.77 | AVPR1A (0.37) | KDM1AAVPR1A | |
| Propane SCHEMBL8890366 | 0.76 | SIGMAR1 (0.51) | AVPR1A | |
| Hexane SCHEMBL8606727 | 0.75 | SIGMAR1 (0.48) | AVPR1A | |
| Pentane SCHEMBL8573177 | 0.75 | SIGMAR1 (0.48) | AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837707-A | USEFUL IN TREATING ANXIETY, PSYCHOSIS, EPILEPSY, CONVULSIONS, AMNESIA, PARKINSON'S DISEASE | H. LUNDBECK A/S (DK) | 1998-11-17 | — | — | US | disclosed |
| US-5830896-A | PSYCHOLOGICAL DISORDERS; ANTIEPILEPIC AGENTS; ALZHEIMER'SAND PARKINSON?S DISEASE | H. LUNDBECK A/S (DK) | 1998-11-03 | — | — | US | disclosed |
| US-5684012-A | TREATMENT OF PSYCHOLOGICAL AND NEUROLOGICAL DISORDERS | H. LUNDBECK A/S (DK) | 1997-11-04 | — | — | US | disclosed |