Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17206979 | 0.75 | GAA (0.51) | GAALMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL13879431 | 0.73 | CYP3A4 (0.50) | GAALMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL9055178 | 0.72 | GAA (0.75) | GAALMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL8765043 | 0.72 | GAA (0.54) | GAALMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL8414045 | 0.72 | TSHR (0.40) | LMNATSHRCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL13879480 | 0.72 | CDC25B (0.42) | ALDH1A1NPSR1KDM4EHPGDHSD17B10 | |
| SCHEMBL10743922 | 0.72 | LARS1 (0.36) | GAALMNACYP1A2CYP2C19ALDH1A1 | |
| Bromide SCHEMBL11612764 | 0.72 | GAA (0.45) | GAALMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11613982 | 0.72 | GAA (0.54) | GAALMNAPOLBCYP1A2CYP2C19 | |
| Iodide SCHEMBL11613376 | 0.72 | GAA (0.45) | GAALMNACYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |