Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416069 | 0.86 | ALDH1A1 (0.42) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8417012 | 0.84 | GAA (0.43) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL8415370 | 0.79 | GAA (0.40) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL8576059 | 0.78 | TDP1 (0.46) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL8683030 | 0.72 | ALOX5 (0.42) | LMNACYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL4653392 | 0.72 | CYP2D6 (0.36) | ALDH1A1LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL8575699 | 0.72 | GAA (0.43) | TSHRNOTUMALDH1A1KLK7KDM4E | |
| SCHEMBL11188819 | 0.70 | MEN1 (0.34) | ALDH1A1LMNAMAPTCYP1A2CYP2C9 | |
| SCHEMBL8558617 | 0.69 | HTR6 (0.42) | NOTUMFAAH | |
| Hydrochloric Acid SCHEMBL10834103 | 0.69 | MEN1 (0.33) | ALDH1A1LMNAMAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880284-A | HAVING ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASES-INHIBITING EFFECTS | DR. KARL THOMAE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5681841-A | PREVENTION CELL AGGREGATION | KARL THOMAE GMBH (DE) | 1997-10-28 | — | — | US | disclosed |