Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59872 | 0.85 | HSD17B10 (0.60) | ALDH1A1HPGDMAPTHSD17B10MAPK1 | |
| Ethane SCHEMBL27801588 | 0.84 | HSD17B10 (0.58) | ALDH1A1HPGDMAPTHSD17B10MAPK1 | |
| Padimate O SCHEMBL5669080 | 0.78 | ALDH1A1 (0.76) | ALDH1A1HPGDMAPTHSD17B10MAPK1 | |
| Oxybenzone SCHEMBL10392134 | 0.78 | HPGD (0.58) | ALDH1A1HPGDMAPTMAPK1PKM | |
| SCHEMBL113328 | 0.78 | TDP1 (0.67) | ALDH1A1HSD17B10MAPK1PKMLMNA | |
| SCHEMBL17978239 | 0.78 | TDP1 (0.67) | ALDH1A1HSD17B10MAPK1PKMLMNA | |
| SCHEMBL29449291 | 0.78 | TDP1 (0.67) | ALDH1A1HSD17B10MAPK1PKMLMNA | |
| Benzoic Acid 1-(3-Methyl)Butyl Ester SCHEMBL132524 | 0.76 | LMNA (0.65) | ALDH1A1HSD17B10MAPK1PKMLMNA | |
| Benzoic Acid 1-(3-Methyl)Butyl Ester SCHEMBL28250108 | 0.76 | LMNA (0.65) | ALDH1A1HSD17B10MAPK1PKMLMNA | |
| SCHEMBL384494 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPTHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5833961-A | CROSSLINKED POLYESTERS AND TWO ORGANIC ACTIVE SUNSCREEN AGENTS; SYNERGISTIC INCREASE IN SOLUBILITY; NON-IRRITATING; WATER REPELLENCY | INOLEX INVESTMENT CORPORATION (US) | 1998-11-10 | — | — | US | disclosed |