Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TK1 | P04183 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510290 | 0.92 | MCHR1 (0.44) | MCHR1ALDH1A1TSHRPLA2G2CSMN1; SMN2 | |
| SCHEMBL6932473 | 0.92 | MCHR1 (0.44) | MCHR1ALDH1A1TSHRPLA2G2CSMN1; SMN2 | |
| SCHEMBL15226646 | 0.88 | FAAH (0.43) | MCHR1ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL15226645 | 0.88 | FAAH (0.43) | MCHR1ALDH1A1TSHRLMNACYP3A4 | |
| SCHEMBL4865763 | 0.79 | G6PD (0.41) | MCHR1ALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL4865752 | 0.79 | G6PD (0.41) | MCHR1ALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL10730061 | 0.79 | MCHR1 (0.43) | MCHR1TSHRPLA2G2CTK1FAAH | |
| SCHEMBL1914562 | 0.79 | MCHR1 (0.43) | MCHR1TSHRPLA2G2CTK1FAAH | |
| SCHEMBL1914559 | 0.79 | MCHR1 (0.43) | MCHR1TSHRPLA2G2CTK1FAAH | |
| SCHEMBL10730052 | 0.79 | MCHR1 (0.43) | MCHR1TSHRPLA2G2CTK1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753707-A | TREATING SKIN DISORDER, DERMATITIS, ROUGH SKIN; BARRIER FUNCTION | KAO CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0761644-A2 | Amide derivatives and their use in cosmetic composition | KAO CORPORATION (JP) | 1997-03-12 | — | — | EP | disclosed |
| EP-0398272-B1 | Amide derivatives and dermatologic preparations containing the same | KAO CORP (JP) | 1994-08-10 | — | — | EP | disclosed |
| US-5221757-A | Maintains normal barrier function of skin's horney layer and restores damaged barrier functions so as to suppress inflammation and chapping | KAO CORPORATION (JP) | 1993-06-22 | — | — | US | disclosed |
| US-5175321-A | Amide alcohols for skins | KAO CORPORATION (JP) | 1992-12-29 | — | — | US | disclosed |