SCHEMBL8575922

SCHEMBL8575922

O=C(O[C@@H]1[C@@H](OC(=O)c2ccccc2)[C@@H](O)O[C@H](CO)[C@H]1OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 6/20 0.60
LGALS9 O00182 5/20 0.60
LGALS1 P09382 5/20 0.60
LGALS7; LGALS7B P47929 4/20 0.60
LGALS8 O00214 3/20 0.45
SELP P16109 4/20 0.43
SELE P16581 1/20 0.41
HK1 P19367 2/20 0.41
HK2 P52789 2/20 0.41
PTPN1 P18031 2/20 0.41
MEN1 O00255 1/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41
KMT2A Q03164 1/20 0.41
MAOB P27338 1/20 0.40
RNASE1 P07998 1/20 0.39
LGALS4 P56470 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8575918 1.00 LGALS3 (0.60) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL2486267 1.00 LGALS3 (0.60) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL8574803 1.00 LGALS3 (0.60) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL8602850 1.00 LGALS3 (0.60) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL715284 0.98 LGALS3 (0.61) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL7744292 0.98 LGALS3 (0.61) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL715283 0.98 LGALS3 (0.61) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL26102195 0.90 LGALS3 (0.70) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL13211174 0.90 LGALS3 (0.70) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL18654301 0.89 LGALS3 (0.50) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998016537-A1 NOVEL COMPOUNDS ASTRA AKTIEBOLAG (PUBL) (SE) 1998-04-23 WO disclosed