SCHEMBL715283

SCHEMBL715283

O=C(O[C@H]1[C@H](OC(=O)c2ccccc2)C(O)O[C@@H]1CO)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 7/20 0.61
LGALS9 O00182 6/20 0.61
LGALS1 P09382 6/20 0.61
LGALS7; LGALS7B P47929 5/20 0.61
LGALS8 O00214 3/20 0.46
SELP P16109 4/20 0.43
HK1 P19367 2/20 0.41
HK2 P52789 2/20 0.41
SELE P16581 1/20 0.41
MEN1 O00255 1/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41
KMT2A Q03164 1/20 0.41
MAOB P27338 1/20 0.41
PTPN1 P18031 1/20 0.41
RNASE1 P07998 1/20 0.40
LGALS4 P56470 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL715284 1.00 LGALS3 (0.61) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL7744292 1.00 LGALS3 (0.61) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL8574803 0.98 LGALS3 (0.60) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL2486267 0.98 LGALS3 (0.60) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL8575918 0.98 LGALS3 (0.60) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL8575922 0.98 LGALS3 (0.60) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL8602850 0.98 LGALS3 (0.60) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL13211174 0.91 LGALS3 (0.70) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL26102195 0.91 LGALS3 (0.70) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8
SCHEMBL10802114 0.90 LGALS3 (0.64) LGALS3LGALS9LGALS1LGALS7; LGALS7BLGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8912319-B2 Synthesis of 2′-deoxy-2′-[18F]fluoro-5-methyl-1-B-D-arabinofuranosyluracil (18F-FMAU) UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2014-12-16 US disclosed
US-20120053337-A1 SYNTHESIS OF 2'-Deoxy-2'-[18F]FLUORO-5-METHYL-1-B-D-ARABINOFURANOSYLURACIL (18F-FMAU) UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2012-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120053337-A1 SYNTHESIS OF 2'-Deoxy-2'-[18F]FLUORO-5-METHYL-1-B-D-ARABINOFURANOSYLURACIL (18F-FMAU) CGAS, RNGTT, ADA LGALS3 2287/4885LGALS9 1459/4885LGALS1 1242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.