Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29192563 | 0.83 | TSHR (0.39) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL137801 | 0.82 | TSHR (0.45) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29192600 | 0.81 | TSHR (0.41) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30357050 | 0.80 | TSHR (0.37) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21728873 | 0.79 | TSHR (0.42) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4637933 | 0.77 | TSHR (0.41) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27512565 | 0.77 | ALDH1A1 (0.42) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7625494 | 0.75 | ALDH1A1 (0.40) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28723020 | 0.75 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19490 | 0.75 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5787686-A | CONTAINING WATER INSOLUBLE AGRICULTURE PESTICIDE | THE DOW CHEMICAL COMPANY (US) | 1998-08-04 | — | — | US | disclosed |
| US-5753766-A | Amphipathic graft copolymers and copolymer compositions and methods of making | THE DOW CHEMICAL COMPANY (US) | 1998-05-19 | — | — | US | disclosed |
| US-5753248-A | Amphipathic graft copolymer pesticide formulation compositions and methods of their use | THE DOW CHEMICAL COMPANY (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0766705-B1 | PREPARATION OF AMPHIPATHIC GRAFT COPOLYMERS, COMPOSITIONS THEREOF, AND METHODS OF THEIR USE | DOW CHEMICAL CO (US) | 1998-05-13 | — | — | EP | disclosed |
| US-5693716-A | Amphipathic graft copolymers and copolymer compositions and methods of making | THE DOW CHEMICAL COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| CN-1159199-A | Novel amphipathic graft copolymers, their prepn., compositions thereof and methods of their use | DOW CHEMICAL CO (US) | 1997-09-10 | — | — | CN | disclosed |
| EP-0766705-A1 | PREPARATION OF AMPHIPATHIC GRAFT COPOLYMERS, COMPOSITIONS THEREOF, AND METHODS OF THEIR USE | THE DOW CHEMICAL COMPANY (US) | 1997-04-09 | — | — | EP | disclosed |
| WO-1996000251-A1 | NOVEL AMPHIPATHIC GRAFT COPOLYMERS, THEIR PREPARATION, COMPOSITIONS THEREOF, AND METHODS OF THEIR USE | THE DOW CHEMICAL COMPANY (US) | 1996-01-04 | — | — | WO | disclosed |