Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 2/20 | 0.45 |
| ▸ | EDNRB | P24530 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483110 | 1.00 | PARP10 (0.48) | PARP10CA1CA2PARP1PARP2 | |
| SCHEMBL8079337 | 1.00 | PARP10 (0.48) | PARP10CA1CA2PARP1PARP2 | |
| SCHEMBL1947261 | 1.00 | PARP10 (0.48) | PARP10CA1CA2PARP1PARP2 | |
| SCHEMBL6229779 | 0.84 | EDNRA (0.54) | CA1CA2MAOAMAPTHPGD | |
| SCHEMBL9258771 | 0.84 | EDNRA (0.54) | CA1CA2MAOAMAPTHPGD | |
| SCHEMBL7293698 | 0.84 | EDNRA (0.54) | CA1CA2MAOAMAPTHPGD | |
| SCHEMBL6228156 | 0.84 | EDNRA (0.54) | CA1CA2MAOAMAPTHPGD | |
| SCHEMBL7144597 | 0.84 | EDNRA (0.54) | CA1CA2MAOAMAPTHPGD | |
| SCHEMBL8503544 | 0.82 | BACE1 (0.52) | CA1CA2MAOAMAPTHPGD | |
| SCHEMBL8856846 | 0.82 | BACE1 (0.52) | CA1CA2MAOAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847122-A | Process for preparing 1,5-benzothiazepine derivative | TANABE SEIYAKU CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| EP-0792876-A2 | Process for preparing 1,5-benzothiazepine derivative | TANABE SEIYAKU CO., LTD. (JP) | 1997-09-03 | — | — | EP | disclosed |