Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 10/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577088 | 0.84 | NAMPT (0.45) | P2RX1P2RX7P2RX4MAPTRXFP1 | |
| SCHEMBL8576416 | 0.82 | P2RX1 (0.42) | P2RX1P2RX7P2RX4TMPRSS4MAPT | |
| SCHEMBL8577947 | 0.78 | P2RX1 (0.60) | P2RX1P2RX7P2RX4TMPRSS4MAPT | |
| SCHEMBL6791269 | 0.69 | PTGS1 (0.59) | PTGS1 | |
| SCHEMBL28258728 | 0.67 | P2RX1 (1.00) | P2RX1P2RX7P2RX4TMPRSS4P2RX3 | |
| SCHEMBL7086952 | 0.67 | PLG (0.53) | RXFP1PTGS1 | |
| SCHEMBL5666099 | 0.67 | P2RX1 (1.00) | P2RX1P2RX7P2RX4TMPRSS4RXFP1 | |
| SCHEMBL7608067 | 0.67 | MTTP (0.54) | PPARG | |
| SCHEMBL7181703 | 0.67 | P2RX1 (0.72) | P2RX1P2RX7P2RX4TMPRSS4RXFP1 | |
| SCHEMBL4263109 | 0.66 | P2RX1 (0.77) | P2RX1P2RX7P2RX4TMPRSS4P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998017636-A1 | PHENYLALANINOL DERIVATIVES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-04-30 | — | — | WO | claimed |