Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 4/20 | 0.53 |
| ▸ | KLK1 | P06870 | 4/20 | 0.53 |
| ▸ | KLK6 | Q92876 | 4/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | IL2 | P60568 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | APOB | P04114 | 1/20 | 0.47 |
| ▸ | MTTP | P55157 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079790 | 0.88 | S1PR1 (0.51) | ITGB1ITGA4PTGS1IL2NPC1 | |
| SCHEMBL6792746 | 0.87 | PTGS1 (0.57) | PTGS1IL2NPC1RAB9ALMNA | |
| SCHEMBL6791269 | 0.86 | PTGS1 (0.59) | KLKB1PTGS1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7086631 | 0.85 | NPC1 (0.54) | PTGS1IL2NPC1RAB9ALMNA | |
| SCHEMBL7133291 | 0.84 | NPC1 (0.56) | PTGS1IL2NPC1RAB9ALMNA | |
| SCHEMBL7087379 | 0.82 | RXFP1 (0.57) | PTGS1IL2NPC1RAB9ALMNA | |
| SCHEMBL28752149 | 0.81 | PDE2A (0.48) | ITGB1ITGA4PTGS1CA12CA1 | |
| SCHEMBL7084075 | 0.81 | CA12 (0.43) | ITGB1ITGA4PTGS1IL2LMNA | |
| SCHEMBL7083755 | 0.81 | RXFP1 (0.56) | PLGKLKB1PTGS1IL2NPC1 | |
| SCHEMBL7079806 | 0.81 | NPC1 (0.49) | ITGB1ITGA4PTGS1IL2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |