Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824680 | 0.78 | TSHR (0.53) | ALDH1A1KDM4ESMN1; SMN2KMT2AGAA | |
| SCHEMBL279655 | 0.77 | ALDH1A1 (0.53) | PBRM1ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL1821844 | 0.77 | PBRM1 (0.45) | PBRM1ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL1574451 | 0.77 | THRB (0.41) | THRBPBRM1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1683823 | 0.77 | THRB (0.46) | THRBPBRM1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7119411 | 0.76 | KDM4E (0.55) | THRBPBRM1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL38573232 | 0.76 | KDM4E (0.55) | THRBPBRM1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7301325 | 0.76 | ALDH1A1 (0.45) | THRBPBRM1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7301332 | 0.76 | THRB (0.50) | THRBPBRM1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8480383 | 0.76 | ALDH1A1 (0.60) | ALDH1A1KDM4ESMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792840-A | SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES | SANKYO COMPANY, LIMITED (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0437016-A2 | Lipid A analogues having immunoactivating and anti-tumour activity | Sankyo Company Limited (JP) | 1991-07-17 | — | — | EP | disclosed |