Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6737892 | 1.00 | TAAR1 (0.42) | TAAR1GLAKCNQ3KCNQ2GRK2 | |
| SCHEMBL5839335 | 0.82 | SLC6A2 (0.43) | TAAR1KCNQ3KCNQ2L3MBTL1SLC6A2 | |
| SCHEMBL8577151 | 0.82 | SLC6A2 (0.43) | TAAR1KCNQ3KCNQ2L3MBTL1SLC6A2 | |
| SCHEMBL6732197 | 0.82 | SLC6A2 (0.43) | TAAR1KCNQ3KCNQ2L3MBTL1SLC6A2 | |
| SCHEMBL6737612 | 0.82 | SLC6A2 (0.43) | TAAR1KCNQ3KCNQ2L3MBTL1SLC6A2 | |
| SCHEMBL6737874 | 0.80 | RAB9A (0.54) | RAB9AKDM4ESMN1; SMN2ALOX5AP | |
| SCHEMBL6737872 | 0.80 | RAB9A (0.54) | RAB9AKDM4ESMN1; SMN2ALOX5AP | |
| SCHEMBL12354198 | 0.78 | KCNQ3 (0.56) | TAAR1KCNQ3KCNQ2L3MBTL1SLC6A2 | |
| SCHEMBL22492062 | 0.78 | KCNQ3 (0.56) | TAAR1KCNQ3KCNQ2L3MBTL1SLC6A2 | |
| SCHEMBL22492058 | 0.78 | KCNQ3 (0.56) | TAAR1KCNQ3KCNQ2L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235830-A1 | Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235830-A1 | Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases | CYP46A1, REN, CYP11B2 | TAAR1 1296/4885GLA 655/4885KCNQ3 3634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.