SCHEMBL8577171

SCHEMBL8577171

Nc1cccc(OCCS(=O)(=O)CCO)c1S(=O)(=O)O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
TTR P02766 1/20 0.33
CYP2C9 P11712 1/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 2/20 0.32
POLB P06746 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
BRCA1 P38398 1/20 0.32
HTT P42858 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GMNN O75496 1/20 0.32
PKM P14618 1/20 0.32
THPO P40225 1/20 0.32
MTOR P42345 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8579261 0.93 CYP1A2 (0.36) CYP1A2CYP2C19TTRCYP2C9ALDH1A1
SCHEMBL8573836 0.84 CYP1A2 (0.49) CYP1A2CYP2C19CYP2C9ALDH1A1LMNA
SCHEMBL8579282 0.78 TTR (0.43) TTRCYP2C9ALDH1A1LMNAPOLB
SCHEMBL8577197 0.77 CYP1A2 (0.51) CYP1A2CYP2C19CYP2C9ALDH1A1LMNA
SCHEMBL8779863 0.76 ALDH1A1 (0.55) CYP1A2CYP2C19TTRCYP2C9ALDH1A1
SCHEMBL8574914 0.75 ALDH1A1 (0.41) CYP1A2CYP2C19CYP2C9ALDH1A1LMNA
SCHEMBL11260729 0.74 IDO1 (0.40) CYP1A2CYP2C19ALDH1A1LMNAPOLB
SCHEMBL11261592 0.74 IDO1 (0.40) CYP1A2CYP2C19ALDH1A1LMNAPOLB
SCHEMBL8079307 0.72 HSD17B10 (0.38) CYP1A2ALDH1A1LMNAPOLBRAB9A
SCHEMBL8086619 0.72 HSD17B10 (0.41) CYP1A2CYP2C9ALDH1A1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744622-A water-soluble, fiber-reactive anthraquinone compounds HOECHST AKTIENGESELLSCHAFT (DE) 1998-04-28 US disclosed