SCHEMBL8577173

SCHEMBL8577173

C1=CCC([Ti+3]Cc2ccccc2)=C1.CC(C)[O-].CC(C)[O-].CC(C)[O-]

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.32
SLC6A2 P23975 2/20 0.32
SIGMAR1 Q99720 2/20 0.32
MAOA P21397 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
CYP2A6 P11509 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
SLC18A2 Q05940 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8575609 0.75
SCHEMBL8580929 0.70
Hydrochloric Acid SCHEMBL2232413 0.68 HRH3 (0.38) TAAR1MAOA
SCHEMBL27519489 0.68 TAAR1 (0.32) TAAR1SLC6A2SIGMAR1MAOASLC6A4
Hydrochloric Acid SCHEMBL4632861 0.64 KCNA3 (0.46) TAAR1
SCHEMBL8576332 0.63
SCHEMBL8577227 0.60 CA1 (0.34) SLC6A4
Hydrochloric Acid SCHEMBL4632231 0.60
SCHEMBL2836936 0.60 CALM1 (0.46) TAAR1SIGMAR1SLC18A2CYP2D6
SCHEMBL7635348 0.60 TP53 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5739225-A CATALYTIC HOMO- OR COPOLYMERIZATION IN PRESENCE OF A MIXTURE COMPRISING A TRANSITION METAL COMPOUND AND AN ALUMOXANE IDEMITSU KOSAN CO., LTD. (JP) 1998-04-14 US disclosed