SCHEMBL8577227

SCHEMBL8577227

CC(C)[O-].CC(C)[O-].CC(C)[O-].COc1ccc([Ti+3]C2=CC=CC2)cc1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA7 P43166 2/20 0.34
CA9 Q16790 2/20 0.34
CA12 O43570 1/20 0.34
CA14 Q9ULX7 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
TAS1R2 Q8TE23 1/20 0.32
SLC6A4 P31645 1/20 0.31
PKM P14618 1/20 0.31
ACHE P22303 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5610235 0.64
SCHEMBL8575609 0.64
SCHEMBL8577173 0.60 TAAR1 (0.32) SLC6A4
SCHEMBL27447384 0.60 CYP1A2 (0.40) CA1CA2CA7CA9CA12
SCHEMBL1974726 0.59
SCHEMBL8580929 0.59
SCHEMBL17236570 0.59 ALDH1A1 (0.45) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL8489 0.59 CA1 (1.00) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL21802643 0.59 CA1 (1.00) CA1CA2CA7CA9CA12
Hydrochloric Acid SCHEMBL5420013 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5739225-A CATALYTIC HOMO- OR COPOLYMERIZATION IN PRESENCE OF A MIXTURE COMPRISING A TRANSITION METAL COMPOUND AND AN ALUMOXANE IDEMITSU KOSAN CO., LTD. (JP) 1998-04-14 US disclosed