Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678033 | 1.00 | RAB9A (0.45) | RAB9ARXFP1KDM4ETP53TSHR | |
| SCHEMBL17443379 | 0.86 | TP53 (0.55) | TP53TSHRMAPTMAOB | |
| SCHEMBL17448042 | 0.85 | TP53 (0.44) | TP53KMT2AMAOB | |
| SCHEMBL7379052 | 0.84 | ALDH1A1 (0.42) | RAB9ARXFP1KDM4ETSHRALDH1A1 | |
| SCHEMBL14378542 | 0.83 | FFAR1 (0.45) | RAB9AKDM4ETSHRALDH1A1KMT2A | |
| SCHEMBL3449610 | 0.83 | FFAR1 (0.45) | RAB9AKDM4ETSHRALDH1A1KMT2A | |
| SCHEMBL14378544 | 0.83 | FFAR1 (0.45) | RAB9AKDM4ETSHRALDH1A1KMT2A | |
| SCHEMBL30047263 | 0.79 | ALDH1A1 (0.52) | KDM4ETSHRALDH1A1MEN1KMT2A | |
| SCHEMBL259951 | 0.79 | ALDH1A1 (0.52) | KDM4ETSHRALDH1A1MEN1KMT2A | |
| SCHEMBL3630406 | 0.79 | KDM4E (0.50) | KDM4ETSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998016527-A1 | BENZOXEPINE DERIVATIVES WHICH PROMOTE RELEASE OF GROWTH HORMONE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-23 | — | — | WO | disclosed |