Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632025 | 0.71 | SMN1; SMN2 (0.33) | HSD17B10SMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL9696498 | 0.70 | — | — | |
| SCHEMBL15329614 | 0.65 | HSD17B10 (0.44) | HSD17B10SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL10973591 | 0.64 | PKM (0.49) | HSD17B10SMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL10970338 | 0.64 | PKM (0.49) | HSD17B10SMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL9332118 | 0.64 | — | — | |
| SCHEMBL8575765 | 0.63 | GAA (0.47) | NPC1RAB9APOLBALDH1A1PKM | |
| SCHEMBL15332741 | 0.63 | PKM (0.44) | HSD17B10SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL11522174 | 0.63 | PKM (0.59) | HSD17B10SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL11522171 | 0.63 | HSD17B10 (0.53) | HSD17B10SMN1; SMN2TP53POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998001035-A1 | THE USE OF 5-ALKYL-1,3,4-OXADIAZOL(AND THIADIAZOL)-2-THIOMETHYLTHIOCYANATES AS MARINE ANTIFOULING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1998-01-15 | — | — | WO | claimed |
| US-5631207-A | ANTIFOULING AGENTS FOR MARINE ENVIRONMENT | THE DOW CHEMICAL COMPANY (US) | 1997-05-20 | — | — | US | claimed |
| WO-1998001035-A1 | THE USE OF 5-ALKYL-1,3,4-OXADIAZOL(AND THIADIAZOL)-2-THIOMETHYLTHIOCYANATES AS MARINE ANTIFOULING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1998-01-15 | — | — | WO | disclosed |
| US-5631207-A | ANTIFOULING AGENTS FOR MARINE ENVIRONMENT | THE DOW CHEMICAL COMPANY (US) | 1997-05-20 | — | — | US | disclosed |