Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577469 | 0.71 | HSD17B10 (0.39) | SMN1; SMN2PKMRAB9ANPC1TP53 | |
| SCHEMBL8669334 | 0.66 | KMT2A (0.37) | SMN1; SMN2TP53HPGDALDH1A1KMT2A | |
| SCHEMBL11321465 | 0.61 | SMN1; SMN2 (0.46) | SMN1; SMN2PKML3MBTL1RAB9ANPC1 | |
| SCHEMBL367218 | 0.60 | — | — | |
| SCHEMBL9394258 | 0.60 | ALDH1A1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL9961014 | 0.60 | NOTUM (0.61) | SMN1; SMN2L3MBTL1RAB9ANPC1HPGD | |
| SCHEMBL27612858 | 0.57 | POLB (0.31) | — | |
| SCHEMBL9058700 | 0.56 | KMT2A (0.56) | SMN1; SMN2RAB9ANPC1TP53HPGD | |
| SCHEMBL11667232 | 0.54 | FAAH (0.32) | TP53 | |
| Potassium Ion SCHEMBL28278916 | 0.54 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998001035-A1 | THE USE OF 5-ALKYL-1,3,4-OXADIAZOL(AND THIADIAZOL)-2-THIOMETHYLTHIOCYANATES AS MARINE ANTIFOULING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1998-01-15 | — | — | WO | disclosed |
| US-5631207-A | ANTIFOULING AGENTS FOR MARINE ENVIRONMENT | THE DOW CHEMICAL COMPANY (US) | 1997-05-20 | — | — | US | disclosed |