Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577637 | 1.00 | KCNH2 (0.37) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| SCHEMBL8577645 | 1.00 | KCNH2 (0.37) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7498763 | 0.99 | KCNH2 (0.37) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7498754 | 0.99 | KCNH2 (0.37) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7505703 | 0.99 | KCNH2 (0.37) | KCNH2SCN5AKDM4EALDH1A1HPGD | |
| SCHEMBL7924434 | 0.89 | KCNH2 (0.38) | KCNH2SCN5AALDH1A1 | |
| SCHEMBL8570562 | 0.88 | SCN5A (0.38) | KCNH2SCN5AKDM4EALDH1A1 | |
| SCHEMBL8570568 | 0.88 | SCN5A (0.38) | KCNH2SCN5AKDM4EALDH1A1 | |
| SCHEMBL8570557 | 0.88 | SCN5A (0.38) | KCNH2SCN5AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7501189 | 0.88 | SCN5A (0.38) | KCNH2SCN5AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | claimed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |