SCHEMBL8577702

SCHEMBL8577702

COC(=O)C(C)Oc1ccc(Oc2ncc(C(F)(F)F)cc2F)cc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.49
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
MAPT P10636 1/20 0.49
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 5/20 0.46
ALDH1A1 P00352 3/20 0.46
LIPE Q05469 1/20 0.44
SCN9A Q15858 1/20 0.43
ATM Q13315 1/20 0.43
FFAR1 O14842 1/20 0.42
ACACB O00763 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9359751 1.00 LMNA (0.49) LMNAKMT2AMEN1L3MBTL1MAPT
SCHEMBL10691274 0.89 LMNA (0.49) LMNAKMT2AMEN1L3MBTL1MAPT
SCHEMBL9194781 0.88 SMN1; SMN2 (0.48) LMNAKMT2AMEN1MAPTSMN1; SMN2
SCHEMBL9397562 0.88 SMN1; SMN2 (0.48) LMNAKMT2AMEN1MAPTSMN1; SMN2
Haloxyfop-P-Methyl SCHEMBL54547 0.88 LMNA (0.65) LMNAKMT2AMEN1L3MBTL1MAPT
Haloxyfop-P-Methyl SCHEMBL54814 0.88 LMNA (0.65) LMNAKMT2AMEN1L3MBTL1MAPT
Haloxyfop-P-Methyl SCHEMBL29370417 0.88 LMNA (0.65) LMNAKMT2AMEN1L3MBTL1MAPT
Haloxyfop-P-Methyl SCHEMBL29514646 0.88 LMNA (0.65) LMNAKMT2AMEN1L3MBTL1MAPT
Hydrochloric Acid SCHEMBL10564555 0.87 SMN1; SMN2 (0.47) LMNAKMT2AMEN1MAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL10564552 0.87 SMN1; SMN2 (0.47) LMNAKMT2AMEN1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE33478-E POSTEEMERGENECE, PREEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1990-12-11 US claimed
EP-0097460-B1 PYRIDYL(OXY/THIO)PHENOXY COMPOUNDS, HERBICIDAL COMPOSITIONS AND METHODS THE DOW CHEMICAL COMPANY (US) 1988-04-06 EP claimed
US-4565568-A Pyridyl(oxy/thio)phenoxy compounds, herbicidal compositions and methods THE DOW CHEMICAL COMPANY (US) 1986-01-21 US claimed
US-5787686-A CONTAINING WATER INSOLUBLE AGRICULTURE PESTICIDE THE DOW CHEMICAL COMPANY (US) 1998-08-04 US disclosed
US-5753766-A Amphipathic graft copolymers and copolymer compositions and methods of making THE DOW CHEMICAL COMPANY (US) 1998-05-19 US disclosed
US-5753248-A Amphipathic graft copolymer pesticide formulation compositions and methods of their use THE DOW CHEMICAL COMPANY (US) 1998-05-19 US disclosed
EP-0766705-B1 PREPARATION OF AMPHIPATHIC GRAFT COPOLYMERS, COMPOSITIONS THEREOF, AND METHODS OF THEIR USE DOW CHEMICAL CO (US) 1998-05-13 EP disclosed
US-5693716-A Amphipathic graft copolymers and copolymer compositions and methods of making THE DOW CHEMICAL COMPANY (US) 1997-12-02 US disclosed
CN-1159199-A Novel amphipathic graft copolymers, their prepn., compositions thereof and methods of their use DOW CHEMICAL CO (US) 1997-09-10 CN disclosed
EP-0439857-B1 A solvent-free process for the preparation of ((pyridinyloxy)phenoxy) propionate derivatives DOWELANCO (US) 1994-12-21 EP disclosed
US-5049675-A Solvent-free process for the preparation of ((pyridinyloxy)phenoxy) propionate derivatives DOWELANCO (US) 1991-09-17 US disclosed
EP-0439857-A2 A solvent-free process for the preparation of ((pyridinyloxy)phenoxy) propionate derivatives DOWELANCO (US) 1991-08-07 EP disclosed
US-4786731-A AMIDATION THE DOW CHEMICAL COMPANY (US) 1988-11-22 US disclosed
EP-0109752-B1 SELECTIVE, BROADSPECTRUM WEED CONTROL IN SOYBEANS THE DOW CHEMICAL COMPANY (US) 1988-06-29 EP disclosed
EP-0097460-B1 PYRIDYL(OXY/THIO)PHENOXY COMPOUNDS, HERBICIDAL COMPOSITIONS AND METHODS THE DOW CHEMICAL COMPANY (US) 1988-04-06 EP disclosed
US-4586949-A BENTAZON AND 3-SUBSTITUTED PYRIDYLOXY(ORTHIO)-PHENOXY ALKANOATE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1986-05-06 US disclosed
EP-0109752-A1 Selective, broadspectrum weed control in soybeans THE DOW CHEMICAL COMPANY (US) 1984-05-30 EP disclosed