Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897620 | 0.84 | GPR84 (0.40) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL5172109 | 0.84 | PTGS1 (0.33) | — | |
| SCHEMBL713526 | 0.83 | TSHR (0.38) | LMNA | |
| SCHEMBL8896477 | 0.82 | GPR84 (0.39) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL8897005 | 0.82 | GPR84 (0.43) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL8895611 | 0.80 | GPR84 (0.42) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL5713075 | 0.80 | GPR84 (0.42) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL8898484 | 0.80 | GPR84 (0.42) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL7159926 | 0.80 | LMNA (0.46) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL6812423 | 0.80 | LMNA (0.46) | LMNACYP2D6SPHK1GMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103232491-B | A kind of preparation method of cyclic phosphoric acid | 河北科技大学 | 2016-06-15 | — | — | CN | claimed |
| CN-102391075-B | Preparation method of 1-aryl-2,2-dimethyl-1,3-propylene glycol | UNIV HEBEI SCIENCE & TECH | 2015-03-25 | — | — | CN | claimed |
| CN-103232491-B | A kind of preparation method of cyclic phosphoric acid | 河北科技大学 | 2016-06-15 | — | — | CN | disclosed |
| CN-103232491-B | A kind of preparation method of cyclic phosphoric acid | 河北科技大学 | 2016-06-15 | — | — | CN | disclosed |
| CN-102391075-B | Preparation method of 1-aryl-2,2-dimethyl-1,3-propylene glycol | UNIV HEBEI SCIENCE & TECH | 2015-03-25 | — | — | CN | disclosed |
| CN-102391075-B | Preparation method of 1-aryl-2,2-dimethyl-1,3-propylene glycol | UNIV HEBEI SCIENCE & TECH | 2015-03-25 | — | — | CN | disclosed |
| CN-102391075-B | Preparation method of 1-aryl-2,2-dimethyl-1,3-propylene glycol | UNIV HEBEI SCIENCE & TECH | 2015-03-25 | — | — | CN | disclosed |
| CN-103232491-A | Preparation method of cyclic phosphoric acid | UNIV HEBEI SCIENCE & TECH | 2013-08-07 | — | — | CN | disclosed |
| CN-102391075-A | Preparation method of 1-aryl-2,2-dimethyl-1,3-propylene glycol | UNIV HEBEI SCIENCE & TECH | 2012-03-28 | — | — | CN | disclosed |
| CN-102391075-A | Preparation method of 1-aryl-2,2-dimethyl-1,3-propylene glycol | UNIV HEBEI SCIENCE & TECH | 2012-03-28 | — | — | CN | disclosed |
| EP-0963972-A2 | Stereoselective reduction of carbonyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1999-12-15 | — | — | EP | disclosed |