Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199413 | 0.82 | GABRA1 (0.57) | CA1CA2CYP1A2CYP3A4KMT2A | |
| SCHEMBL141647 | 0.80 | CA1 (0.60) | LPAR1HDAC4HDAC8KCNK3KCNK9 | |
| SCHEMBL31257131 | 0.80 | CA1 (0.60) | LPAR1HDAC4HDAC8KCNK3KCNK9 | |
| SCHEMBL714182 | 0.79 | CA1 (0.58) | HDAC4HDAC8CA1CA2CA12 | |
| Ammonia Solution, Strong SCHEMBL28077841 | 0.78 | CA1 (0.57) | LPAR1HDAC4HDAC8KCNK3KCNK9 | |
| SCHEMBL714204 | 0.78 | CA1 (0.50) | HDAC4HDAC8CA1CA2CA12 | |
| SCHEMBL2737350 | 0.77 | LPAR1 (0.45) | LPAR1HDAC4HDAC8KCNK3KCNK9 | |
| SCHEMBL683593 | 0.77 | NFE2L2 (0.47) | LPAR1HDAC4HDAC8KCNK3KCNK9 | |
| SCHEMBL7816151 | 0.77 | KDM4E (0.47) | LPAR1HDAC4HDAC8KCNK3KCNK9 | |
| SCHEMBL13913509 | 0.75 | KCNK3 (0.46) | LPAR1HDAC4HDAC8KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798362-A | USEFUL AS ALPHA-ADRENORECEPTOR BLOCKERS; CONDENSATION | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1998-08-25 | — | — | US | claimed |