Acridine

Acridine

SCHEMBL8577853

CCCCN(CCCC)CCCC.c1ccc2nc3ccccc3cc2c1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.58
GLA P06280 1/20 0.58
MAPT P10636 1/20 0.58
HPGD P15428 1/20 0.58
ACHE P22303 1/20 0.58
TLR8 Q9NR97 7/20 0.51
BCHE P06276 2/20 0.49
HTR1B P28222 1/20 0.47
ELANE P08246 1/20 0.45
ATP4A P20648 1/20 0.45
ATP4B P51164 1/20 0.45
HTR3A P46098 1/20 0.44
DRD2 P14416 1/20 0.44
OPRM1 P35372 1/20 0.44
DRD3 P35462 1/20 0.44
OPRD1 P41143 1/20 0.44
OPRK1 P41145 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acridine SCHEMBL29014290 0.88 ALDH1A1 (0.68) ALDH1A1GLAMAPTHPGDACHE
Acridine SCHEMBL28232031 0.86 ALDH1A1 (0.65) ALDH1A1GLAMAPTHPGDACHE
Acridine SCHEMBL27681561 0.86 ALDH1A1 (0.65) ALDH1A1GLAMAPTHPGDACHE
Acridine SCHEMBL28205217 0.84 ALDH1A1 (0.62) ALDH1A1GLAMAPTHPGDACHE
Acridine SCHEMBL25416084 0.81 ALDH1A1 (0.54) ALDH1A1GLAMAPTHPGDACHE
Acridine SCHEMBL27710856 0.79 ALDH1A1 (0.56) ALDH1A1GLAMAPTHPGDACHE
Acridine SCHEMBL2331753 0.77 ALDH1A1 (0.71) ALDH1A1GLAMAPTHPGDACHE
Acridine SCHEMBL28832684 0.77 ALDH1A1 (0.58) ALDH1A1GLAMAPTHPGDACHE
Acridine SCHEMBL8339 0.76 ALDH1A1 (1.00) ALDH1A1GLAMAPTHPGDACHE
Acridine SCHEMBL29352289 0.76 ALDH1A1 (1.00) ALDH1A1GLAMAPTHPGDACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998013311-A1 CORROSION INHIBITING COMPOSITION FOR TREATING ASBESTOS CONTAINING MATERIALS W.R. GRACE & CO.-CONN. (US) 1998-04-02 WO disclosed