Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576660 | 0.84 | KMT2A (0.41) | KMT2AADCY8POLBSIGMAR1ALDH1A1 | |
| SCHEMBL8578448 | 0.84 | SMN1; SMN2 (0.34) | KMT2APOLBL3MBTL1KDM4EPSEN1 | |
| SCHEMBL13548018 | 0.83 | PSEN1 (0.34) | POLBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13548004 | 0.83 | POLB (0.36) | KMT2APOLBALDH1A1MEN1L3MBTL1 | |
| SCHEMBL18958947 | 0.83 | KMT2A (0.49) | KMT2AADCY8SIGMAR1ALDH1A1HTT | |
| SCHEMBL8574296 | 0.83 | ALDH1A1 (0.39) | KMT2APOLBSIGMAR1ALDH1A1MEN1 | |
| SCHEMBL8577976 | 0.83 | KMT2A (0.40) | KMT2AADCY8SIGMAR1ALDH1A1HTT | |
| SCHEMBL8575823 | 0.83 | KMT2A (0.40) | KMT2AADCY8SIGMAR1ALDH1A1HTT | |
| SCHEMBL8579607 | 0.80 | ALDH1A1 (0.41) | KMT2AADCY8SIGMAR1ALDH1A1HTT | |
| SCHEMBL8580842 | 0.80 | ADCY8 (0.39) | KMT2AADCY8SIGMAR1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719310-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | disclosed |
| US-5610122-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |