Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577784 | 0.91 | HPN (0.46) | ALOX15HPNMAPTSIRT5PTGS1 | |
| SCHEMBL9190675 | 0.88 | HPN (0.46) | ALOX15HPNMAPTSIRT5PTGS1 | |
| SCHEMBL9190670 | 0.87 | ALOX15 (0.52) | ALOX15HPNMAPTSIRT5PTGS1 | |
| SCHEMBL8578891 | 0.87 | ALOX15 (0.52) | ALOX15HPNMAPTSIRT5PTGS1 | |
| SCHEMBL7516430 | 0.83 | ALDH1A1 (0.42) | ALOX15HPNMAPTSIRT5PTGS1 | |
| SCHEMBL9190111 | 0.83 | ALOX15 (0.55) | ALOX15HPNMAPTSIRT5PTGS1 | |
| SCHEMBL5692047 | 0.80 | ALOX15 (0.55) | ALOX15HPNMAPTSIRT5PTGS1 | |
| SCHEMBL8576913 | 0.79 | ALOX15 (0.47) | ALOX15HPNMAPTSIRT5PTGS1 | |
| SCHEMBL8944903 | 0.79 | HPN (0.44) | ALOX15HPNMAPTSIRT5PTGS1 | |
| SCHEMBL8578022 | 0.79 | HPN (0.41) | ALOX15HPNMAPTSIRT5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795876-A | ANTIINFLAMMATORY AGENTS | HOECHST MARION ROUSSSEL, INC. (US) | 1998-08-18 | — | — | US | disclosed |