Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548016 | 0.74 | ALDH1A1 (0.63) | LMNASMN1; SMN2POLBCYP1A2CYP2D6 | |
| SCHEMBL31131321 | 0.74 | LMNA (0.45) | LMNASMN1; SMN2POLBCYP1A2CYP2D6 | |
| SCHEMBL20708485 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL5883517 | 0.72 | LMNA (0.44) | LMNASMN1; SMN2POLBCYP1A2CYP2D6 | |
| SCHEMBL2466602 | 0.70 | LMNA (0.62) | LMNASMN1; SMN2POLBCYP1A2CYP2D6 | |
| SCHEMBL31611880 | 0.61 | ALDH1A1 (0.56) | LMNASMN1; SMN2POLBCYP1A2CYP2D6 | |
| Hydrazine SCHEMBL11361257 | 0.60 | KMT2A (0.53) | LMNASMN1; SMN2POLBCYP1A2CYP2D6 | |
| SCHEMBL1947332 | 0.59 | ALDH1A1 (0.39) | SMN1; SMN2CYP1A2CYP2D6MAPTHTT | |
| SCHEMBL169281 | 0.59 | ALDH1A1 (1.00) | SMN1; SMN2MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL31607672 | 0.59 | ALDH1A1 (1.00) | SMN1; SMN2MAPTGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786121-A | DISSOLVING IN SOLVENT MIXTURE OF PENTAFLUOROPROPIONIC ACID AND ONE OF HALOGENATED ALKANE OR HALOGENATED AROMATIC, OPTIONALLY IN COMBINATION WITH A SULFONIC ACID | Syntec Gesellschaft fur Chemie und Technologie der Informationsaufzeichnu ng mbH (DE) | 1998-07-28 | — | — | US | disclosed |