Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28136682 | 0.88 | TSHR (0.43) | TP53NR1H2NR1H3TSHRTRPA1 | |
| SCHEMBL8616446 | 0.81 | TP53 (0.48) | TP53NR1H2NR1H3TSHRTRPA1 | |
| SCHEMBL15302665 | 0.79 | TP53 (0.46) | TP53NR1H2NR1H3TSHRTRPA1 | |
| SCHEMBL3503476 | 0.79 | TP53 (0.46) | TP53NR1H2NR1H3TSHRTRPA1 | |
| SCHEMBL4514772 | 0.78 | TSHR (0.43) | TP53NR1H2NR1H3TSHRTRPA1 | |
| SCHEMBL679387 | 0.78 | TSHR (0.43) | TP53NR1H2NR1H3TSHRTRPA1 | |
| SCHEMBL16378246 | 0.78 | TP53 (0.48) | TP53NR1H2NR1H3TSHRTRPA1 | |
| SCHEMBL14838179 | 0.76 | TP53 (0.48) | TP53NR1H2NR1H3TSHRTRPA1 | |
| SCHEMBL2286891 | 0.75 | NR1H2 (0.39) | TP53NR1H2NR1H3TSHRTRPA1 | |
| SCHEMBL11740122 | 0.74 | TP53 (0.46) | TP53NR1H2NR1H3TSHRTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203644-A1 | Compositions for treating and/or preventing diseases characterized by the presence of metal ions | GRENPHARMA LLC (US) | 2009-08-13 | — | — | US | disclosed |
| US-5808112-A | Preparation of cis-4-O-protected-2-cyclopentenol derivatives | HOECHST MARION ROUSSEL INC. (US) | 1998-09-15 | — | — | US | disclosed |
| CN-1179770-A | Preparation of cis- 4 -0 -protected -2 -cyclopentenol derivatives | HOECHST MARION ROUSSEL INC (US) | 1998-04-22 | — | — | CN | disclosed |
| US-5728899-A | Preparation of cis-4-O-protected-2-cyclopentenol derivatives | HOECHST MARION ROUSSEL INC. (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0817764-A1 | PREPARATION OF CIS-4-O-PROTECTED-2-CYCLOPENTENOL DERIVATIVES | HOECHST MARION ROUSSEL, INC. (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030320-A1 | PREPARATION OF CIS-4-O-PROTECTED-2-CYCLOPENTENOL DERIVATIVES | HOECHST MARION ROUSSEL, INC. (US) | 1996-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203644-A1 | Compositions for treating and/or preventing diseases characterized by the presence of metal ions | APP, PSEN1, IAPP | TP53 241/4885NR1H2 4304/4885NR1H3 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.