Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28136682 | 0.84 | TSHR (0.43) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL4514772 | 0.84 | TSHR (0.43) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL10945537 | 0.82 | GRIN2D (0.35) | ESR1TDP1ALDH1A1 | |
| SCHEMBL8577993 | 0.78 | TP53 (0.44) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL16378246 | 0.78 | TP53 (0.48) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL231005 | 0.78 | ESR1 (0.56) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL1107767 | 0.78 | TP53 (0.48) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL4526742 | 0.78 | TSHR (0.48) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL9622630 | 0.78 | TSHR (0.48) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL379345 | 0.78 | TSHR (0.48) | TSHRTP53NR1H2NR1H3CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7347970-B2 | Biocides based on silanol terminated silanes and siloxanes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-03-25 | — | — | US | claimed |
| US-20060194764-A1 | Biocides based on silanol terminated silanes and siloxanes | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2006-08-31 | — | — | US | claimed |
| WO-2006028491-A1 | BIOCIDES BASED ON SILANOL TERMINATED SILANES AND SILOXANES | UNIVERSITY OF FLORIDA (US) | 2006-03-16 | — | — | WO | claimed |
| EP-0378706-B1 | 5-SUBSTITUTED URIDINE DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION | TAIHO PHARMACEUTICAL CO LTD (JP) | 1994-12-28 | — | — | EP | claimed |
| EP-0378706-A1 | 5-SUBSTITUTED URIDINE DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1990-07-25 | — | — | EP | claimed |
| CN-120040492-A | Method for synthesizing silanol by catalyzing and oxidizing silane with polyacid | 辽宁科技大学 | 2025-05-27 | — | — | CN | disclosed |
| US-12227529-B2 | Method of preparing silanols with selective cytochrome P450 variants and related compounds and compositions | DOW SILICONES CORPORATION (US) | 2025-02-18 | — | — | US | disclosed |
| CN-119119106-A | Method for preparing silanol by selective oxidation of hydrosilane under catalysis of nano porous palladium copper | 大连理工大学 | 2024-12-13 | — | — | CN | disclosed |
| WO-2023222245-A1 | PROCESS FOR PRODUCING ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2023-11-23 | — | — | WO | disclosed |
| CN-114262341-B | Method for preparing silanol by photocatalytic oxidation of silane | 西安交通大学 | 2023-05-02 | — | — | CN | disclosed |
| US-20230102728-A1 | METHOD OF PREPARING SILANOLS WITH SELECTIVE CYTOCHROME P450 VARIANTS AND RELATED COMPOUNDS AND COMPOSITIONS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2023-03-30 | — | — | US | disclosed |
| US-20230102728-A1 | METHOD OF PREPARING SILANOLS WITH SELECTIVE CYTOCHROME P450 VARIANTS AND RELATED COMPOUNDS AND COMPOSITIONS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2023-03-30 | — | — | US | disclosed |
| US-5420117-A | Antitumor agents | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0378706-B1 | 5-SUBSTITUTED URIDINE DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION | TAIHO PHARMACEUTICAL CO LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5200488-A | POLYORGANOSILOXANE HAVING A QUATERNARY SALT AT ITS ONE TERMINAL AND PERCUTANEOUS ABSORPTION-PROMOTING AGENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1993-04-06 | — | — | US | disclosed |
| EP-0484857-A2 | Polyorganosiloxane having a quaternary salt at its one terminal and percutaneous absorption-promoting agent | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-05-13 | — | — | EP | disclosed |
| EP-0378706-A1 | 5-SUBSTITUTED URIDINE DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1990-07-25 | — | — | EP | disclosed |
| EP-0377175-A2 | Pattern forming composition and process for forming pattern using the same | HITACHI, LTD. (JP) | 1990-07-11 | — | — | EP | disclosed |
| US-4315032-A | ANTITHROMBOGENIC AGENTS, ANTIULCER AGENTS | TEITIN LIMITED (JP) | 1982-02-09 | — | — | US | disclosed |
| EP-0019475-A2 | Process for preparing adjacently disubstituted ketones, novel prostaglandins E1 and anti-thrombotic compositions containing them | TEIJIN LIMITED (JP) | 1980-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230102728-A1 | METHOD OF PREPARING SILANOLS WITH SELECTIVE CYTOCHROME P450 VARIANTS AND RELATED COMPOUNDS AND COMPOSITIONS | CYP2E1, POR, CYP3A43 | TSHR 4817/4885TP53 1108/4885NR1H2 85/4885 |
| US-20060194764-A1 | Biocides based on silanol terminated silanes and siloxanes | MSR1, S1PR3, TAS2R3 | TSHR 438/4885TP53 2863/4885NR1H2 439/4885 |
| US-12227529-B2 | Method of preparing silanols with selective cytochrome P450 variants and related compounds and compositions | CYP2E1, POR, CYP3A43 | TSHR 4817/4885TP53 1108/4885NR1H2 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.