Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679387 | 0.84 | TSHR (0.43) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL28136682 | 0.84 | TSHR (0.43) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL3503476 | 0.80 | TP53 (0.46) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL8577993 | 0.78 | TP53 (0.44) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL1107767 | 0.78 | TP53 (0.48) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL9622630 | 0.78 | TSHR (0.48) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL16378246 | 0.78 | TP53 (0.48) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL231005 | 0.78 | ESR1 (0.56) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL4526742 | 0.78 | TSHR (0.48) | TSHRTP53NR1H2NR1H3CALM1 | |
| SCHEMBL379345 | 0.78 | TSHR (0.48) | TSHRTP53NR1H2NR1H3CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994711-B2 | Condensation-curable silicone composition and a semiconductor device | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-06-12 | — | — | US | disclosed |
| US-9862803-B2 | Branched organopolysiloxane and a method for preparing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-01-09 | — | — | US | disclosed |
| US-9587075-B2 | Addition-curable silicone composition and a semiconductor device | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-03-07 | — | — | US | disclosed |
| US-20160304675-A1 | BRANCHED ORGANOPOLYSILOXANE AND A METHOD FOR PREPARING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-10-20 | — | — | US | disclosed |
| US-20160304673-A1 | ADDITION-CURABLE SILICONE COMPOSITION AND A SEMICONDUCTOR DEVICE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-10-20 | — | — | US | disclosed |
| US-20160280959-A1 | CONDENSATION-CURABLE SILICONE COMPOSITION AND A SEMICONDUCTOR DEVICE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-09-29 | — | — | US | disclosed |
| US-8791221-B2 | Addition-curable metallosiloxane compound | DAICEL CORPORATION (JP) | 2014-07-29 | — | — | US | disclosed |
| EP-2650319-A1 | ADDITION-CURABLE METALLOSILOXANE COMPOUND | Daicel Corporation (JP) | 2013-10-16 | — | — | EP | disclosed |
| US-20130267653-A1 | ADDITION-CURABLE METALLOSILOXANE COMPOUND | DAICEL CORPORATION (JP) | 2013-10-10 | — | — | US | disclosed |
| CN-103249762-A | Addition-curable metallosiloxane compound | DAICEL CORP | 2013-08-14 | — | — | CN | disclosed |
| US-7507480-B2 | Corrosion-resistant metal surfaces | BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) | 2009-03-24 | — | — | US | disclosed |
| US-20060269760-A1 | Corrosion-resistant metal surfaces | ENERGY, UNITED STATES DEPARTMENT OF | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267653-A1 | ADDITION-CURABLE METALLOSILOXANE COMPOUND | B2M, MSI2, MNS1 | TSHR 4702/4885TP53 3501/4885NR1H2 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.