Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CRHR1 | P34998 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2876218 | 1.00 | KDM4E (0.51) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| SCHEMBL21753931 | 0.91 | KDM4E (0.61) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| SCHEMBL1715255 | 0.87 | KDM4E (0.61) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| SCHEMBL29555008 | 0.87 | KDM4E (0.61) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| Zinc Ion SCHEMBL1714876 | 0.87 | KDM4E (0.61) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| SCHEMBL1714432 | 0.87 | KDM4E (0.61) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| SCHEMBL4557363 | 0.83 | KDM4E (0.47) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| SCHEMBL4564694 | 0.81 | KDM4E (0.48) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| SCHEMBL7201185 | 0.80 | KDM4E (0.47) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| 8-Hydroxy Quinaldine SCHEMBL2878876 | 0.80 | METAP2 (0.47) | TDP1CYP1A2SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891121-A1 | ORGANIC ELECTROLUMINESCENT ELEMENTS | TDK Corporation (JP) | 1999-01-13 | — | — | EP | disclosed |