Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555008 | 0.96 | KDM4E (0.61) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| SCHEMBL1715255 | 0.96 | KDM4E (0.61) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| SCHEMBL21753931 | 0.96 | KDM4E (0.61) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| Zinc Ion SCHEMBL1714876 | 0.96 | KDM4E (0.61) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| SCHEMBL2876218 | 0.87 | KDM4E (0.51) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| SCHEMBL8578296 | 0.87 | KDM4E (0.51) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| 2-Phenylphenol SCHEMBL29555689 | 0.83 | KDM4E (0.48) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| SCHEMBL4564694 | 0.83 | KDM4E (0.48) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| 2-Phenylphenol SCHEMBL4564710 | 0.83 | KDM4E (0.48) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 | |
| SCHEMBL7201185 | 0.82 | KDM4E (0.47) | KDM4ETDP1CRHR1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486549-B1 | ORGANIC ELECTROLUMINESCENT ELEMENT | TOYOTA JIDOSHOKKI KK (JP) | 2012-01-11 | — | — | EP | disclosed |
| EP-1755362-B1 | ORGANIC EL DEVICE | TOYOTA JIDOSHOKKI KK (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-7854998-B2 | Organic EL devices | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2010-12-21 | — | — | US | disclosed |
| EP-1489154-B1 | ORGANIC ELECTROLUMINESCENCE DEVICE | TOYOTA JIDOSHOKKI KK (JP) | 2009-05-13 | — | — | EP | disclosed |
| US-7521567-B2 | Amine compound and uses thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2009-04-21 | — | — | US | disclosed |
| US-20080290788-A1 | Organic el Devices | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2008-11-27 | — | — | US | disclosed |
| US-7419727-B2 | Organic electroluminescent device | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2008-09-02 | — | — | US | disclosed |
| US-7338720-B2 | Organic electroluminescent element | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2008-03-04 | — | — | US | disclosed |
| US-7252892-B2 | Organic electroluminescence device | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2007-08-07 | — | — | US | disclosed |
| EP-1755362-A1 | ORGANIC EL DEVICE | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2007-02-21 | — | — | EP | disclosed |
| US-20070018568-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2007-01-25 | — | — | US | disclosed |
| US-20060228577-A1 | Organic electroluminescent device | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2006-10-12 | — | — | US | disclosed |
| US-20060226421-A1 | Amine compound and uses thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KENKYUJO (JP) | 2006-10-12 | — | — | US | disclosed |
| US-20060192473-A1 | Organic electroluminescent device | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1599074-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-11-23 | — | — | EP | disclosed |
| EP-1560469-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Kabushiki Kaisha Toyota Jidoshokki (JP) | 2005-08-03 | — | — | EP | disclosed |
| US-20050089713-A1 | Organic electroluminescent element | KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) | 2005-04-28 | — | — | US | disclosed |
| US-20050084707-A1 | Organic electroluminescence device | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2005-04-21 | — | — | US | disclosed |
| EP-1489154-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2004-12-22 | — | — | EP | disclosed |
| EP-1486549-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2004-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060226421-A1 | Amine compound and uses thereof | PNMT, TYR, PAM | KDM4E 260/4885TDP1 2733/4885CRHR1 4679/4885 |
| US-20050084707-A1 | Organic electroluminescence device | ELAVL1, SELE, CELF2 | KDM4E 2019/4885TDP1 2108/4885CRHR1 4805/4885 |
| US-20050089713-A1 | Organic electroluminescent element | SOD3, CELF2, SOD1 | KDM4E 2269/4885TDP1 2575/4885CRHR1 4701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.