Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813450 | 0.83 | PARP1 (0.53) | CYP3A4SMN1; SMN2DHODHPARP1TSHR | |
| Ethylene Glycol SCHEMBL28673949 | 0.78 | CYP3A4 (0.44) | CYP3A4SMN1; SMN2DHODHPARP1TSHR | |
| SCHEMBL8580796 | 0.76 | CA12 (0.48) | SMN1; SMN2TSHRMAPTHSD17B10TDP1 | |
| SCHEMBL20127846 | 0.75 | DHODH (0.47) | CYP3A4SMN1; SMN2DHODHPARP10PARP3 | |
| SCHEMBL8580804 | 0.74 | CA5A (0.50) | SMN1; SMN2POLBMAPTL3MBTL1KMT2A | |
| SCHEMBL8583415 | 0.74 | PARP10 (0.55) | CYP3A4PARP1TSHRPOLBMAPT | |
| SCHEMBL24160674 | 0.73 | PARP10 (0.42) | CYP3A4SMN1; SMN2DHODHPARP1TSHR | |
| SCHEMBL5174897 | 0.73 | DHODH (0.50) | CYP3A4SMN1; SMN2DHODHPARP1TSHR | |
| SCHEMBL1498158 | 0.72 | DHODH (0.65) | CYP3A4SMN1; SMN2DHODHPARP1TSHR | |
| SCHEMBL1807480 | 0.72 | PARP1 (0.58) | CYP3A4SMN1; SMN2DHODHPARP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792840-A | SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES | SANKYO COMPANY, LIMITED (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0437016-A2 | Lipid A analogues having immunoactivating and anti-tumour activity | Sankyo Company Limited (JP) | 1991-07-17 | — | — | EP | disclosed |