Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579775 | 1.00 | AAK1 (0.37) | AAK1SLC7A5CTSLCTSBCTSS | |
| SCHEMBL8577090 | 0.86 | SLC7A5 (0.41) | SLC7A5CPA1SLC1A3SLC1A2RNPEP | |
| SCHEMBL8577100 | 0.86 | SLC7A5 (0.41) | SLC7A5CPA1SLC1A3SLC1A2RNPEP | |
| SCHEMBL8575312 | 0.81 | CYP1A2 (0.33) | SLC1A3SLC1A2 | |
| SCHEMBL8575315 | 0.81 | CYP1A2 (0.33) | SLC1A3SLC1A2 | |
| SCHEMBL27766846 | 0.77 | AAK1 (0.34) | AAK1SLC7A5 | |
| SCHEMBL6078689 | 0.76 | AAK1 (0.38) | AAK1SLC7A5CTSLCTSBCTSS | |
| SCHEMBL67031 | 0.76 | AAK1 (0.48) | AAK1SLC7A5CTSLCTSBCTSS | |
| SCHEMBL69223 | 0.76 | AAK1 (0.48) | AAK1SLC7A5CTSLCTSBCTSS | |
| SCHEMBL29013205 | 0.76 | MEN1 (0.33) | AAK1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840712-A | TARGETS AND LINKERS | RECEPTAGEN CORPORATION (US) | 1998-11-24 | — | — | US | disclosed |