Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575315 | 1.00 | CYP1A2 (0.33) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3626322 | 0.88 | CYP1A2 (0.38) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL26129393 | 0.88 | CYP1A2 (0.38) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL26129394 | 0.88 | CYP1A2 (0.38) | CYP1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8579779 | 0.81 | AAK1 (0.37) | SLC1A3SLC1A2 | |
| SCHEMBL8579775 | 0.81 | AAK1 (0.37) | SLC1A3SLC1A2 | |
| SCHEMBL20514701 | 0.79 | MEN1 (0.37) | CYP1A2MEN1KMT2AGAAHDAC1 | |
| SCHEMBL20514700 | 0.79 | MEN1 (0.37) | CYP1A2MEN1KMT2AGAAHDAC1 | |
| SCHEMBL8764441 | 0.79 | KMT2A (0.39) | MEN1KMT2AGAAHDAC1HDAC2 | |
| SCHEMBL30669496 | 0.79 | ENPEP (0.37) | CYP1A2GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840712-A | TARGETS AND LINKERS | RECEPTAGEN CORPORATION (US) | 1998-11-24 | — | — | US | disclosed |