Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.60 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.47 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | FCER2 | P06734 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628545 | 1.00 | PIN1 (0.60) | PIN1ACEPTPN1EPHX2CTSS | |
| SCHEMBL7394440 | 0.81 | PIN1 (0.60) | PIN1CTSSCTSKCTSBPSMB5 | |
| SCHEMBL4969559 | 0.81 | PIN1 (0.47) | PIN1PSMB5PSMB8FCER2 | |
| SCHEMBL3512251 | 0.78 | KDM4A (0.54) | EPHX2 | |
| SCHEMBL1519731 | 0.77 | CTSS (0.74) | ACEPTPN1CTSSCTSKCTSB | |
| SCHEMBL29401906 | 0.77 | CTSS (0.74) | ACEPTPN1CTSSCTSKCTSB | |
| SCHEMBL29397962 | 0.77 | CTSS (0.74) | ACEPTPN1CTSSCTSKCTSB | |
| SCHEMBL29436862 | 0.77 | CTSS (0.74) | ACEPTPN1CTSSCTSKCTSB | |
| SCHEMBL8658551 | 0.77 | ACE (0.58) | ACEPTPN1CTSSCTSKCTSB | |
| SCHEMBL3821361 | 0.77 | CTSS (0.74) | ACEPTPN1CTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998016527-A1 | BENZOXEPINE DERIVATIVES WHICH PROMOTE RELEASE OF GROWTH HORMONE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-23 | — | — | WO | disclosed |