Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | FABP3 | P05413 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12929982 | 0.82 | POLB (0.42) | POLBGAAGFERLMNAALDH1A1 | |
| SCHEMBL16248039 | 0.81 | GABRA1 (0.37) | POLBGAAGFERGABRA1GABRB2 | |
| SCHEMBL16450517 | 0.80 | GABRA1 (0.34) | POLBGAAGFERGABRA1GABRB2 | |
| SCHEMBL12326178 | 0.80 | ACHE (0.44) | POLBGAAGFERALDH1A1MEN1 | |
| SCHEMBL26328949 | 0.79 | POLB (0.39) | POLBGAAGFERLMNAALDH1A1 | |
| SCHEMBL29824511 | 0.74 | HDAC4 (0.51) | POLBGAAGFERALDH1A1MEN1 | |
| SCHEMBL11436435 | 0.73 | HDAC4 (0.44) | POLBGAAGFERMEN1KMT2A | |
| SCHEMBL12993780 | 0.73 | CA1 (0.37) | POLBGAAGFERALDH1A1MEN1 | |
| SCHEMBL10177355 | 0.73 | POLB (0.41) | POLBGAAGFERMEN1KMT2A | |
| SCHEMBL10177330 | 0.73 | POLB (0.41) | POLBGAAGFERALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763436-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | claimed |