Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | PTGFR | P43088 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696155 | 1.00 | TBXA2R (0.41) | TBXA2RLMNAALDH1A1PTGER1PTGFR | |
| SCHEMBL6690724 | 0.91 | PDE4D (0.49) | TBXA2RLMNAALDH1A1PTGER1PTGFR | |
| SCHEMBL8579034 | 0.91 | PDE4D (0.49) | TBXA2RLMNAALDH1A1PTGER1PTGFR | |
| SCHEMBL6690486 | 0.91 | PDE4D (0.49) | TBXA2RLMNAALDH1A1PTGER1PTGFR | |
| SCHEMBL6691982 | 0.91 | PTGFR (0.48) | TBXA2RLMNAALDH1A1PTGER1PTGFR | |
| SCHEMBL6694985 | 0.91 | PDE4D (0.35) | ALDH1A1PDE4D | |
| SCHEMBL6693745 | 0.90 | PDE4D (0.48) | TBXA2RLMNAALDH1A1PTGER3PTGER4 | |
| SCHEMBL7598676 | 0.82 | LMNA (0.59) | TBXA2RLMNAALDH1A1PTGER1PTGFR | |
| SCHEMBL6691950 | 0.82 | PDE4D (0.42) | TBXA2RLMNAALDH1A1PTGER1PTGFR | |
| SCHEMBL8430735 | 0.81 | ALDH1A1 (0.52) | TBXA2RLMNAALDH1A1PTGER1PTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798378-A | TREATMENT OF OCULAR HYPERTENSION | ALLERGAN (US) | 1998-08-25 | — | — | US | disclosed |