Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 11/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675429 | 0.76 | APP (0.55) | APPGRM5MAPTHNF4AASIC3 | |
| SCHEMBL8579924 | 0.76 | CYP1A1 (0.41) | — | |
| SCHEMBL2114741 | 0.75 | APP (0.92) | APPGRM5MAPTHNF4ACA12 | |
| Diphenylacetylene SCHEMBL27628902 | 0.75 | APP (0.92) | APPGRM5MAPTHNF4AASIC3 | |
| SCHEMBL7526751 | 0.74 | GRM5 (0.56) | APPGRM5MAPTHNF4AASIC3 | |
| SCHEMBL6364777 | 0.73 | APP (0.75) | APPGRM5MAPTHNF4AASIC3 | |
| Diphenylacetylene SCHEMBL27913124 | 0.72 | APP (0.86) | APPGRM5MAPTHNF4AASIC3 | |
| SCHEMBL7997661 | 0.72 | GRM5 (0.55) | APPGRM5MAPTHNF4AASIC3 | |
| SCHEMBL8577931 | 0.72 | GRM5 (0.61) | APPGRM5MAPTHNF4AFFAR1 | |
| SCHEMBL8909968 | 0.72 | GRM5 (0.65) | APPGRM5MAPTHNF4ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705578-A | Method for making and using a supported metallocene catalyst system | PHILLIPS PETROLEUM COMPANY (US) | 1998-01-06 | — | — | US | claimed |
| US-5830958-A | Polynuclear metallocene preparation and use | PHILLIPS PETROLEUM COMPANY (US) | 1998-11-03 | — | — | US | disclosed |
| US-5705578-A | Method for making and using a supported metallocene catalyst system | PHILLIPS PETROLEUM COMPANY (US) | 1998-01-06 | — | — | US | disclosed |