Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582606 | 0.88 | KDM4E (0.37) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8581792 | 0.85 | CMA1 (0.42) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8580855 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8584161 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8582476 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8585559 | 0.84 | KDM4E (0.34) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8581511 | 0.82 | KDM4E (0.36) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8580686 | 0.81 | KDM4E (0.35) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL27367144 | 0.81 | SLC9A1 (0.32) | TSHR | |
| SCHEMBL8532443 | 0.79 | SLC9A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |