Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.32 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27370527 | 0.86 | TSHR (0.31) | SLC9A1SLC9A2TSHR | |
| SCHEMBL27447733 | 0.86 | TSHR (0.31) | SLC9A1SLC9A2TSHR | |
| SCHEMBL8532443 | 0.85 | SLC9A1 (0.46) | SLC9A1SLC9A2 | |
| SCHEMBL27351351 | 0.85 | TSHR (0.30) | TSHR | |
| SCHEMBL27351350 | 0.84 | — | — | |
| SCHEMBL8580346 | 0.81 | KDM4E (0.37) | TSHR | |
| SCHEMBL27366156 | 0.74 | — | — | |
| SCHEMBL27439069 | 0.74 | — | — | |
| SCHEMBL8529735 | 0.73 | SLC9A1 (0.44) | SLC9A1SLC9A2 | |
| SCHEMBL27439064 | 0.73 | THRA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1055920-C | Alkyl benzoylguanidines derivatives | MERCK PATENT GMBH (DE) | 2000-08-30 | — | — | CN | disclosed |
| CN-1128753-A | Alkyl benzoylguanidines derivatives | MERCK PATENT GMBH (DE) | 1996-08-14 | — | — | CN | disclosed |