Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582608 | 0.96 | CNR2 (0.38) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL8585560 | 0.95 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL8582770 | 0.92 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL8581795 | 0.85 | CMA1 (0.40) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL8581008 | 0.84 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL8581514 | 0.84 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL8580648 | 0.84 | CNR2 (0.41) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL8582478 | 0.84 | METAP2 (0.37) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL8580856 | 0.84 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 | |
| SCHEMBL8581811 | 0.82 | CMA1 (0.39) | ALDH1A1KDM4EHPGDMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |